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筑药网:高质量的PROTAC分子砌块、ADC Linkers、寡核苷酸药物研发分子砌块供应商

2024-06-13

PROTAC类分子砌块产品.jpg

筑药网是一家医药中间体研发定制和销售的平台,致力于满足医药研发领域的多样化需求。我们深知医药研发过程中对高质量原料的严格要求,因此,专注于为客户提供高质量的苯环中间体、嘧啶中间体、杂环中间体现货产品,以及PROTAC、寡核苷酸和ADC药物研发所需的分子砌块产品及定制服务。

PROTAC分子砌块
PROTAC Building Blocks and ADC Linkes

PROTAC(蛋白降解靶向嵌合体)技术是当前药物研发的热点。我们提供相关分子砌块,支持研发人员设计和优化PROTAC分子,以实现对疾病相关蛋白的靶向降解。

筑药网提供超过600种的Linker和E3连接酶配体砌块,涵盖了常见的长碳链、乙二醇长链、螺杂环链,CRBN、VHL、cIAP和MDM2配体等多种化学结构。
Pharmalego offers over 600 types of linkers and E3 ligase ligand building blocks, covering a variety of chemical structures, including common long carbon chains, ethylene glycol chains, spiro heterocycle chains, and ligands for CRBN, VHL, cIAP, and MDM2.

E3 Ligase-CRBN>100
E3 Ligase-VHL>100
E3 Ligase-others >50
PROTAC linker>1000

ADC Linkers

我们拥有R&D实验室和高活性药物生产能力,科研团队拥有专业丰富的化学修饰技术和能力,在库毒素和连接子可以为客户满足从毫克到千克级研发需求,助力客户的ADC药物研发需求。
We have R&D laboratories and high-potency drug production capabilities. Our research team is highly skilled in chemical modification techniques and capabilities. Our library of toxins and linkers can meet clients' research needs from milligrams to kilograms, supporting their ADC drug development requirements.

ADC linkers>300
Toxins>50
Payloads>30

寡核苷酸药物研发分子砌块
Oligonucleotides Building Blocks

筑药网(Pharmalego)可以高效快捷地提供单体和递送系统的定制和研发服务。目前我们拥有 300 多个合成砌块 ,可以对单体的核糖、碱基、磷酸骨架进行修饰改造,也可以对递送系统进行修饰和改造,包括 GalNAc 和 LNP 的修饰和改造。
Pharmalego can provide custom synthesis and R&D services for monomers and delivery systems efficiently and promptly. Currently, we have over 300 synthetic building blocks, enabling modifications of the ribose, base, and phosphate backbone of monomers. Additionally, we can modify and optimize delivery systems, including GalNAc and LNP.

寡核苷酸药物研发分子砌块.jpg

医药中间体
Pharmaceutical Intermediates

筑药网(Pharmalego)的医药中间体产品涵盖面广,分类繁多,包含苯环类中间体、嘧啶类中间体、吡啶类中间体以及各种杂环类中间体等,为客户提供优质高纯度的中间体从而达到缩短得到目标产物的时间,满足客户的不同需求。
Pharmalego offers a wide range of pharmaceutical intermediates, encompassing a variety of categories including benzene ring intermediates, pyrimidine intermediates, pyridine intermediates, and various heterocyclic intermediates. We provide high-quality, high-purity intermediates to help clients shorten the time required to obtain target products and meet the diverse needs of our clients.

Benzene intermediates
Pyrimidine intermediates
Pyridine intermediates
Various Heterocyclic intermediates

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